Johnson & Johnson Surgical Vision – Irvine Campus
Irvine, CA
J&J Surgical Vision global HQ; manufactures TECNIS intraocular lens (IOL) insertion systems; R&D for cataract surgery devices; 1,600+ employees; acquired via Abbott Medical Optics 2017
Johnson & Johnson Vision Care – Jacksonville Campus
Jacksonville, FL
Manufactures >1.7 billion ACUVUE brand contact lenses annually; ~90% of US supply; $1B+ expansion announced June 2026 to add new distribution facility in NW Jacksonville; R&D also on site
Ethicon – Cornelia Manufacturing Plant
Cornelia, GA
Founded 1946; produces majority of world's supply of surgical sutures; supplies raw suture materials to other Ethicon plants; 500–999 employees; active as of 2024
DePuy Synthes – Warsaw Campus
Warsaw, IN
Original DePuy manufacturing site founded 1895; manufactures joint reconstruction implants (hip, knee), orthopaedic instruments; ~1,100 employees
DePuy Synthes – Raynham Campus
Raynham, MA
DePuy Synthes Spine manufacturing, R&D, and US commercial operations; spine implants and instruments including thoracolumbar, cervical, and minimally invasive systems; also DePuy Mitek sports medicine
Johnson & Johnson – Holly Springs NC Biologics Facility at FUJIFILM Diosynth Campus
Holly Springs, NC
$2B, 10-year commitment for dedicated 160,000 sq ft suite at FUJIFILM Diosynth Biotechnologies' biopharmaceutical campus; operational fall 2025; ~120 new jobs; biologic medicines production
Johnson & Johnson – Wilson NC Biologics Manufacturing Facility (under construction)
Wilson, NC
$2B investment; 500,000 sq ft biologics manufacturing for oncology, immunology, neuroscience, and cardiopulmonary medicines; groundbreaking March 2025; operational target 2028; 500+ permanent jobs
Johnson & Johnson – Wilson NC Drug Product Manufacturing Facility (2nd site, under construction)
Wilson, NC
Second multibillion-dollar facility in Wilson County announced Jan 2026; state-of-the-art drug product manufacturing for oncology and neurological diseases; ~500 additional jobs
Janssen Pharmaceuticals / J&J Innovative Medicine – Raritan Campus
Raritan, NJ
Primary US pharmaceutical manufacturing and supply-chain operations for Janssen; oral solid dosage and API production; part of the largest J&J NJ footprint
Ethicon Endo-Surgery – Cincinnati/Blue Ash Campus
Cincinnati, OH
Ethicon Endo-Surgery global HQ and manufacturing/R&D; makes HARMONIC ultrasonic energy devices, ENSEAL advanced bipolar energy, and minimally invasive surgical tools; ~1,400 employees
Janssen Biotech – Horsham Campus
Horsham, PA
Biologics manufacturing for Remicade (infliximab), Stelara (ustekinumab), Simponi, Doxil, Zytiga; 1,000–4,999 employees; key US biotech production site for Janssen
Johnson & Johnson – Lower Gwynedd Cell Therapy Facility (under construction)
Lower Gwynedd, PA
$1B+ next-generation cell therapy manufacturing facility announced Feb 2026; 154-acre parcel; operated by Janssen Biotech; 500 biomanufacturing jobs; expected operational 2031
Janssen Biotech – Malvern Campus
Malvern, PA
Biologics manufacturing site; monoclonal antibody and API production; founded as Centocor Biotech in early 1980s; now Janssen Biotech Inc.
DePuy Synthes – West Chester Campus
West Chester, PA
DePuy Synthes (formerly Synthes Inc.) US operations hub; manufacturing and R&D for trauma, spine (craniomaxillofacial), and surgical instruments; acquired by J&J in 2012
Johnson & Johnson / Ethicon Endo Surgery – Guaynabo Facility
Guaynabo, PR
Ethicon Endo Surgery LLC manufacturing and J&J International offices; produces surgical instruments, optical and medical devices; also serves as sales/marketing hub for Puerto Rico operations
Janssen Ortho LLC – Gurabo Pharmaceutical Manufacturing
Gurabo, PR
Founded 1981; two plants on same campus (Janssen Ortho + Janssen-Cilag Manufacturing); oral solid dosage manufacturing and API production; makes Xarelto, Prezista, Nucynta ER; one of two global launch sites for OSD; continuous manufacturing approved by FDA
Janssen Ortho – Manatí Plant (converted to Ethicon MedTech)
Manatí, PR
$168M investment 2024; refurbished former Janssen pharmaceutical facility converted to Ethicon MedTech production; produces sutures, hemostats, and wound closure devices; ~300 new jobs created; 100,000 sq ft expansion
Ethicon LLC – San Lorenzo Manufacturing Plant
San Lorenzo, PR
Primary Ethicon MedTech manufacturing hub in Puerto Rico; ~1,500 employees; produces surgery, orthopedic, and vision products; sutures, mesh, and medical devices; key supply base for J&J MedTech
Ethicon Endo-Surgery – El Paso Manufacturing Plant
El Paso, TX
Ethicon Endo-Mech and Energy (EM&E) manufacturing plant; produces endoscopic mechanical and energy surgical devices; zip code 79910; active as of 2025-2026
Ethicon – San Angelo Manufacturing Plant
San Angelo, TX
Opened 1964; produces ~80% of world's surgical sutures; also makes hemostats and Dermabond; 300,000 sq ft; celebrated 60th anniversary August 2024