Merck Animal Health – Millsboro
Millsboro, DE
Center of excellence for veterinary biologics; three integrated campuses; manufactures vaccines for bovine, swine, poultry, companion animals (cats, dogs, equine); one of world's largest poultry vaccine producers; USDA- and EU (VMD)-certified; 300+ employees.
Merck Wilmington Biotech (under construction)
Wilmington, DE
$1B, 470,000 sq ft biologics center of excellence; groundbreaking April 2025; will produce next-generation biologics, Keytruda (pembrolizumab), and antibody-drug conjugates (ADCs); lab operational by 2028, production of investigational compounds by 2030; 500+ planned full-time roles.
Merck Animal Health – Ames
Ames, IA
Located in Iowa State University Research Park; Animal Health vaccine manufacturing for livestock (swine, poultry) and companion animals; four-year strategic alliance with Iowa State University for innovation in animal health.
Merck Animal Health – De Soto Biologics
De Soto, KS
Animal Health biologics manufacturing; produces large-molecule vaccines and biologic products (fill and freeze-dry); $895M expansion announced May 2025 ($860M manufacturing + $35M R&D labs) adding 200,000 sq ft; part of Kansas City animal health corridor.
Merck Animal Health – Baton Rouge (Allflex Ear Tag)
Baton Rouge, LA
Formerly veterinary medicine manufacturing site; converted in 2022 to Allflex Livestock Intelligence ear tag production (RFID and visual ID tags for cattle traceability); operational since September 2022; up to 33 employees at full capacity.
Merck Animal Health – Worthington
Worthington, MN
Animal Health manufacturing and supply; produces vaccines and treatments for livestock and companion animals; USDA- and EU-certified site supporting worldwide markets.
Merck Maurice R. Hilleman Center for Vaccine Manufacturing – Durham
Durham, NC
262-acre site in Treyburn Corporate Park; manufactures Gardasil/Gardasil 9 (HPV), measles, mumps, rubella, and varicella vaccines; $1B, 225,000 sq ft new facility opened March 2025 (Maurice R. Hilleman Center); advanced data analytics, generative AI, 3D printing, digital twin capabilities.
Merck Manufacturing – Wilson
Wilson, NC
Filling and packaging plant; produces RotaTeq (rotavirus vaccine) filling/packaging; also packaging operations for Gardasil/Gardasil 9 HPV vaccines; expanded multiple times including $57M and $680M investments with Durham.
Merck Animal Health – Elkhorn Manufacturing
Elkhorn, NE
Animal Health manufacturing; 300+ professionals; produces companion animal vaccines and livestock vaccines for dogs, cats, horses, cattle, swine, poultry, farmed fish; over 50 of Merck's 350+ licensed vaccines manufactured here; includes R&D, Regulatory Affairs, Biotechnology.
Merck West Point Manufacturing & R&D Campus
West Point, PA
Merck's largest US manufacturing facility; 400-acre site; manufactures pharmaceuticals and vaccines (including MMR, varicella, Gardasil, Zostavax); also houses core translational medicine, discovery, preclinical and clinical R&D in infectious diseases, vaccine discovery, and neuroscience.
Merck Las Piedras Operations
Las Piedras, PR
Built 1985; one of only two Merck global sites dedicated to new product development and launch; produces Belsomra, Atozet, Janumet, Ribavirin, Clarinex, Temodar, Zetia, Segluromet among others; distributes to 75 countries; 500+ employees including Carolina commercial site.
Merck Animal Health – Dallas/DFW (Allflex Ear Tag)
Dallas, TX
Allflex Livestock Intelligence ear tag production facility near DFW Airport; manufactures RFID and visual livestock identification ear tags for cattle; primary US ear tag site alongside the Baton Rouge facility.
Merck Stonewall Manufacturing Site – Elkton
Elkton, VA
Operating since 1941; 1.2M sq ft complex, 1,000+ employees; current production of small molecule APIs and drug products including HPV vaccine intermediates; $3B Center of Excellence expansion (400,000 sq ft) broke ground October 2025 for additional API and drug product manufacturing; also known as 'Stonewall site'.